South America Holidays

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    Better together

    Save up to AU$703 when you book a flight and hotel together*
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    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
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    Plan, book, and manage your trip all in one place

Top destinations in South America

Bank of Brazil Cultural Center showing heritage architecture and street scenes as well as a large group of people
FlightsFlightsHotelsHotels

Sao Paulo

Sao Paulo

Our pick of the best South America Hotel Deals

Rochester Classic

Rochester Classic

3.5 out of 5
Esmeralda 542, Buenos Aires, Capital Federal
Fully refundableReserve now, pay when you stay
The price is AU$109 per night from 7 Sept to 8 Sept
AU$109
7 Sept - 8 Sept
Rochester Classic
Regal Pacific Buenos Aires

Regal Pacific Buenos Aires

4.5 out of 5
25 De Mayo, 764, Buenos Aires, Capital Federal
Fully refundableReserve now, pay when you stay
Get rates
Regal Pacific Buenos Aires
Concorde Hotel

Concorde Hotel

3 out of 5
25 De Mayo 630, Buenos Aires, Capital Federal
Get rates
Concorde Hotel
See all 115,153 properties in South America
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
All Inclusive Holidays
Cheap Holidays
Cheap Holidays
Cheap Holidays
beach holidays
Beach Holidays
Beach Holidays

Frequently asked questions

If I'm not able to travel, can I cancel my South America vacation package?
It's good to know that you can cancel your South America booking if your plans have changed. Whether you'll be charged a fee or not depends on your airline, hotel or car rental company. It may be possible to cancel or change your booking for free if you booked in the last 24 hours. Visit our Customer Service Portal to learn more.
When is the best time of year to visit South America?
If keeping expenses to a minimum is a priority, is the best time to escape to South America. is usually the priciest month, so you'll need a bigger travel budget if you visit then. are the peak season months and when this destination is often at its most exciting. Clear space in your calendar for if you'd prefer a quieter escape.
How far in advance should I book my South America vacation?
It's hard to pick the ideal time for airfares, but we usually say the earlier, the better. Most international journeys on Expedia become available to compare up to a year in advance. If you're booking at the last minute, don't despair. Cheap prices appear from time to time just weeks before departure dates.
What should I know before booking a South America travel package?
A Expedia travel package can be customized for your budget and is a great way to stretch your dollars further. How little or much you include is your call. Hotels, rental cars and flights — decide on a combination that works with your plans.
Can I travel to South America right now?
For all the information you need about visiting South America, head to our Covid-19 Travel Advisor. Covering travel restrictions, quarantine policies and more, Expedia will help make your trip planning as stress-free as possible.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.